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ICSMA-25-224-01: Santesoft Sante PACS Server ↗ source

August 12, 2025 CISA ICS Medical Advisory

Summary

Successful exploitation of these vulnerabilities could allow an attacker to create arbitrary files, cause a denial-of-service condition, obtain sensitive information, and steal a user's cookie information. CVE-2025-0572: Sante PACS Server Web Portal allows remote attackers utilize DCM files to create arbitrary files on affected installations of Sante PACS Server. CVE-2025-53948: The Sante PACS Server allows a remote attacker to crash the main thread by sending a crafted HL7 message, causing a denial-of-service condition. The application would require a manual restart and no authentication is required. CVE-2025-54156: The Sante PACS Server Web Portal sends credential information without encryption. CVE-2025-54862: Sante PACS Server web portal is vulnerable to stored cross-site scripting. An attacker could inject malicious HTML codes redirecting a user to a malicious webpage and stealing the user's cookie. CVE-2025-54759: Sante PACS Server is vulnerable to stored cross-site scripting. An attacker could inject malicious HTML codes redirecting a user to a malicious webpage and stealing the user's cookie.

Advisory Details CISA ICS CSAF feed

Advisory ID
ICSMA-25-224-01
Status
Final · version 1
Initial release
2025-08-12
Last revised
2025-08-12
Vendor
Santesoft
Critical infrastructure sectors
Healthcare and Public Health
Deployed
Worldwide
Vendor headquarters
Cyprus

CISA also recommends users take the following measures to protect themselves from social engineering attacks:

Do not click web links or open attachments in unsolicited email messages.

Refer to Recognizing and Avoiding Email Scams for more information on avoiding email scams.

Refer to Avoiding Social Engineering and Phishing Attacks for more information on social engineering attacks.

No known public exploitation specifically targeting these vulnerabilities has been reported to CISA at this time.

Credit: Chizuru Toyama (TXOne Networks)

Affected products (1)
  • Sante PACS Server — <4.2.3

From CISA's machine-readable CSAF 2.0 advisory (JSON).

Vulnerabilities as Stated by the Advisory

CVEWeaknessCVSS v3Details
CVE-2025-53948 CWE-415 Double Free 7.5 High The Sante PACS Server allows a remote attacker to crash the main thread by sending a crafted HL7 message, causing a denial-of-service condition. The application would require a manual restart and no authentication is required.

Mitigation: Santesoft recommends users update PACS Server to Version 4.2.3 or later. ↗

Affected, fixed & timeline

Affected:

  • Sante PACS Server <4.2.3
CVE-2025-54156 CWE-319 Cleartext Transmission of Sensitive Information 7.4 High The Sante PACS Server Web Portal sends credential information without encryption.

Mitigation: Santesoft recommends users update PACS Server to Version 4.2.3 or later. ↗

Affected, fixed & timeline

Affected:

  • Sante PACS Server <4.2.3
CVE-2025-54759 CWE-79 Improper Neutralization of Input During Web Page Generation ('Cross-site Scripting') 6.1 Medium Sante PACS Server is vulnerable to stored cross-site scripting. An attacker could inject malicious HTML codes redirecting a user to a malicious webpage and stealing the user's cookie.

Mitigation: Santesoft recommends users update PACS Server to Version 4.2.3 or later. ↗

Affected, fixed & timeline

Affected:

  • Sante PACS Server <4.2.3
CVE-2025-54862 CWE-79 Improper Neutralization of Input During Web Page Generation ('Cross-site Scripting') 5.4 Medium Sante PACS Server web portal is vulnerable to stored cross-site scripting. An attacker could inject malicious HTML codes redirecting a user to a malicious webpage and stealing the user's cookie.

Mitigation: Santesoft recommends users update PACS Server to Version 4.2.3 or later. ↗

Affected, fixed & timeline

Affected:

  • Sante PACS Server <4.2.3
CVE-2025-0572 CWE-22 Improper Limitation of a Pathname to a Restricted Directory ('Path Traversal') 4.3 Medium Sante PACS Server Web Portal allows remote attackers utilize DCM files to create arbitrary files on affected installations of Sante PACS Server.

Mitigation: Santesoft recommends users update PACS Server to Version 4.2.3 or later. ↗

Affected, fixed & timeline

Affected:

  • Sante PACS Server <4.2.3

Scores and weakness types are as CISA or the republishing vendor stated them in this advisory; the linked CVE pages carry the independently enriched CVSS and SSVC assessments.

News Coverage

No coverage found in monitored research blogs or news feeds.

CVEs Referenced in This Publication

CVECVSSAffected
CVE-2025-54156 9.1 Critical Santesoft Sante PACS Server The Sante PACS Server Web Portal sends credential information without encryption.
CVE-2025-53948 8.7 High Santesoft Sante PACS Server The Sante PACS Server allows a remote attacker to crash the main thread by sending a crafted HL7 message, causing a denial-of-service condition. The …
CVE-2025-54759 5.1 Medium Santesoft Sante PACS Server Sante PACS Server is vulnerable to stored cross-site scripting. An attacker could inject malicious HTML codes redirecting a user to a malicious webpa…
CVE-2025-54862 4.8 Medium Santesoft Sante PACS Server Sante PACS Server web portal is vulnerable to stored cross-site scripting. An attacker could inject malicious HTML codes redirecting a user to a mali…
CVE-2025-0572 4.3 Medium Sante PACS Server Sante PACS Server Web Portal DCM File Parsing Directory Traversal Arbitrary File Write Vulnerability. This vulnerability allows remote attackers to c…

Named by the advisory itself. Each CVE links to its tracked detail page.

Vendors Named in This Publication

No KEV-catalogued vendors are named in this publication.